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THSD7A Polyklonaler Antikörper

THSD7A Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28524-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using THSD7A Polyclonal antibody (28524-1-AP)

    WB analysis using 28524-1-AP (same clone as 28524-1-PBS)

    mouse kidney tissue was subjected to SDS PAGE followed by western blot with 28524-1-AP (THSD7A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28524-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28524-1-PBS bindet in WB, Indirect ELISA THSD7A und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen THSD7A fusion protein Ag29107
Vollständiger Name thrombospondin, type I, domain containing 7A
Berechnetes Molekulargewicht 185 kDa
Beobachtetes Molekulargewicht240-250 kDa
GenBank-ZugangsnummerNM_015204
Gene symbol THSD7A
Gene ID (NCBI) 221981
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Thrombospondin type-1 domain-containing protein 7A (THSD7A) is a membrane-associated N-glycoprotein with a molecular weight of 250 kDa, which can be cleaved to release a 210-kDa soluble form (PMID: 22194972; 27214550). THSD7A has a role in angiogenesis. It mediates endothelial cell migration and tube formation (PMID: 2002048). THSD7A has been identified as a second autoantigen involved in adult idiopathic membranous nephropathy in addition to PLA2R1 (PMID: 25394321).