TIAR Monoklonaler Antikörper

TIAR Monoklonal Antikörper für WB, IHC, IF/ICC, FC (Intra), Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, FC (Intra), Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1E8D12

Kat-Nr. : 66907-1-PBS

Synonyme

TIAL1, 1E8D12, Nucleolysin TIAR, TCBP, TIA 1 related protein



Geprüfte Anwendungen

Produktinformation

66907-1-PBS bindet in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA TIAR und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen TIAR fusion protein Ag11981
Vollständiger Name TIA1 cytotoxic granule-associated RNA binding protein-like 1
Berechnetes Molekulargewicht 42 kDa
Beobachtetes Molekulargewicht 39 and 41 kDa
GenBank-ZugangsnummerBC030025
Gene symbol TIAR
Gene ID (NCBI) 7073
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TIAR, also named as TIA 1 related protein, is an RNA-binding protein which is associated with apoptosis. It has been shown that mouse with disrupted TIAR gene show high levels of embryonic lethality. TIAR plays an important role in cytoplasm and nucleus where it can control translation of some specific mRNAs and activate splicing of exons with weak 5-splice sites. 66907-1-Ig detects 39 and 41 kDa bands in SDS-PAGE. Besides, TIAR also has the 28 kDa and 50 kDa proteins for TIAR exists in multiple alternative splicing forms.(PMID: 12533540, 7533298, 22851315, 8176212)