TIAR Monoklonaler Antikörper
TIAR Monoklonal Antikörper für WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
1E8D12
Kat-Nr. : 66907-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66907-1-PBS bindet in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA TIAR und zeigt Reaktivität mit human, Maus, Ratten
Getestete Reaktivität | human, Maus, Ratte |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | TIAR fusion protein Ag11981 |
Vollständiger Name | TIA1 cytotoxic granule-associated RNA binding protein-like 1 |
Berechnetes Molekulargewicht | 42 kDa |
Beobachtetes Molekulargewicht | 39 and 41 kDa |
GenBank-Zugangsnummer | BC030025 |
Gene symbol | TIAR |
Gene ID (NCBI) | 7073 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
TIAR, also named as TIA 1 related protein, is an RNA-binding protein which is associated with apoptosis. It has been shown that mouse with disrupted TIAR gene show high levels of embryonic lethality. TIAR plays an important role in cytoplasm and nucleus where it can control translation of some specific mRNAs and activate splicing of exons with weak 5-splice sites. 66907-1-Ig detects 39 and 41 kDa bands in SDS-PAGE. Besides, TIAR also has the 28 kDa and 50 kDa proteins for TIAR exists in multiple alternative splicing forms.(PMID: 12533540, 7533298, 22851315, 8176212)