TINP1 Polyklonaler Antikörper

TINP1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16230-1-PBS

Synonyme

HUSSY-29, HUSSY29, HCL G1, Hairy cell leukemia protein 1, Hairy cell leukemia

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  WB analysis using 16230-1-AP (same clone as 16230-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16230-1-AP (TINP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16230-1-PBS in a different storage buffer formulation.

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  WB analysis of Caco-2 using 16230-1-AP (same clone as 16230-1-PBS)

  Caco-2 cells were subjected to SDS PAGE followed by western blot with 16230-1-AP (TINP1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16230-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 16230-1-AP (same clone as 16230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 16230-1-AP (TINP1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16230-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 16230-1-AP (same clone as 16230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 16230-1-AP (TINP1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16230-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 16230-1-AP (same clone as 16230-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 16230-1-AP (TINP1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16230-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

16230-1-PBS bindet in WB, IHC, Indirect ELISA TINP1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TINP1 fusion protein Ag8822
• Vollständiger Name: TGF beta-inducible nuclear protein 1
• Berechnetes Molekulargewicht: 260 aa, 30 kDa
• Beobachtetes Molekulargewicht: 30 kDa
• GenBank-Zugangsnummer: BC005288
• Gene symbol: TINP1
• Gene ID (NCBI): 10412
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TINP1 (TGF beta inducible nuclear protein 1) was widely expressed in various cell lines. TINP1 overexpression significantly promoted tumor cell proliferation, which may be associated with the downregulation of p53 expression. Furthermore, TINP1 promoted a number of cell lines to the S phase of the cell cycle. TINP1 promotes cell proliferation and significantly reduces p53 and p21 expression.