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TIPIN Polyklonaler Antikörper

TIPIN Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11972-2-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using TIPIN Polyclonal antibody (11972-2-AP)

    WB analysis using 11972-2-AP (same clone as 11972-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11972-2-AP (TIPIN antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11972-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

11972-2-PBS bindet in WB, Indirect ELISA TIPIN und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TIPIN fusion protein Ag2595
Vollständiger Name TIMELESS interacting protein
Berechnetes Molekulargewicht 301 aa, 34 kDa
Beobachtetes Molekulargewicht 48 kDa
GenBank-ZugangsnummerBC000870
Gene symbol TIPIN
Gene ID (NCBI) 54962
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TIPIN, also named as TIMELESS-interacting protein, is a 301 amino acid protein, which belongs to the CSM3 family. TIPIN Plays an important role in the control of DNA replication and the maintenance of replication fork stability. TIPIN forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress. The calculated molecular weight of TIPIN is 34 kDa, but the result of WB is 55-60 kDa, which is similar to the result of publication.(PMID: 24830473)