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TLE4 Polyklonaler Antikörper

TLE4 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30959-1-PBS

Synonyme

GRG4, KIAA1261

Filter:
  • Western Blot (WB) analysis of various lysates using TLE4 Polyclonal antibody (30959-1-AP)

    WB analysis using 30959-1-AP (same clone as 30959-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30959-1-AP (TLE4 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30959-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of K-562 cells using TLE4 Polyclonal antibody (30959-1-AP)

    IP experiment of K-562 using 30959-1-AP (same clone as 30959-1-PBS)

    IP result of anti-TLE4 (IP:30959-1-AP, 4ug; Detection:30959-1-AP 1:800) with K-562 cells lysate 1720 ug. This data was developed using the same antibody clone with 30959-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30959-1-PBS bindet in WB, IP, Indirect ELISA TLE4 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TLE4 fusion protein Ag34006
Vollständiger Name transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
Berechnetes Molekulargewicht 84 kDa
Beobachtetes Molekulargewicht76-88 kDa
GenBank-ZugangsnummerBC059405
Gene symbol TLE4
Gene ID (NCBI) 7091
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TLE4 (Transducin-like enhancer protein 4), also known as GRG4. It is predicted to be located in the nucleus. Tle4 promotes acquisition of corticothalamic identity and blocks emergence of core characteristics of subcerebral/corticospinal projection neuron identity, including gene expression and connectivity. During the first post-natal week, when corticothalamic innervation is ongoing, Tle4 is required to stabilize corticothalamic neuron identity, limiting interference from differentiation programs of developmentally related neuron classes (PMID: 37561632). The molecular weight of TLE4 is 76 kDa.