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TLR3/CD283 Polyklonaler Antikörper

TLR3/CD283 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17766-1-PBS

Synonyme

TLR3, CD283, toll like receptor 3, Toll-like receptor 3

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  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using TLR3/CD283 Polyclonal antibody (17766-1-AP)

    IHC staining of human tonsillitis using 17766-1-AP (same clone as 17766-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 17766-1-AP (TLR3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17766-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human tonsillitis tissue using TLR3/CD283 Polyclonal antibody (17766-1-AP)

    IHC staining of human tonsillitis using 17766-1-AP (same clone as 17766-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 17766-1-AP (TLR3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17766-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17766-1-PBS bindet in IHC, Indirect ELISA TLR3/CD283 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TLR3/CD283 fusion protein Ag12171
Vollständiger Name toll-like receptor 3
Berechnetes Molekulargewicht 904 aa, 104 kDa
GenBank-ZugangsnummerBC094737
Gene symbol TLR3
Gene ID (NCBI) 7098
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TLR3 belongs to the Toll-like receptor family which is important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR3 is a nucleotide-sensing TLR that is activated by double-stranded RNA. Upon recognition of dsRNA, TLR3 transmits signals via the adaptor protein TICAM-1/TRIF, leading to the induction of type I IFN, cytokine/chemokine production, and dendritic cell (DC) maturation (PMID: 18262679).