TLR5 Monoklonaler Antikörper
TLR5 Monoklonal Antikörper für WB, IF/ICC, FC (Intra), ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
Hausschwein, human, Maus, Ratte
Anwendung
WB, IF/ICC, FC (Intra), ELISA
Konjugation
Unkonjugiert
CloneNo.
4B3D2
Kat-Nr. : 66570-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66570-1-PBS bindet in WB, IF/ICC, FC (Intra), ELISA TLR5 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten
Getestete Reaktivität | Hausschwein, human, Maus, Ratte |
Wirt / Isotyp | Maus / IgG1 |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | TLR5 fusion protein Ag13840 |
Vollständiger Name | toll-like receptor 5 |
Berechnetes Molekulargewicht | 858 aa, 98 kDa |
Beobachtetes Molekulargewicht | 100 kDa |
GenBank-Zugangsnummer | BC109119 |
Gene symbol | TLR5 |
Gene ID (NCBI) | 7100 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-G-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
TLR5 belongs to the Toll-like receptor family which are important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR5 is known to recognize bacterial flagellin from invading mobile bacteria. TLR5 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Mutations in TLR5 gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.