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TLR6 Rekombinanter Antikörper

TLR6 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241926A1

Kat-Nr. : 84811-1-PBS

Synonyme

241926A1, CD286, toll like receptor 6, Toll-like receptor 6

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using TLR6 Recombinant antibody (84811-1-RR)

    WB analysis of mouse brain using 84811-1-RR (same clone as 84811-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 84811-1-RR (TLR6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84811-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84811-1-PBS bindet in WB, Indirect ELISA TLR6 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name toll-like receptor 6
Berechnetes Molekulargewicht 480 aa, 56 kDa
Beobachtetes Molekulargewicht100 kDa
GenBank-ZugangsnummerBC111755
Gene symbol TLR6
Gene ID (NCBI) 10333
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TLR6, also known as CD286, belongs to the Toll-like receptor (TLR) family which is important in the innate immune response to pathogens. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. TLR6 can form a heterodimer with TLR2. TLR6 and TLR2 are both recruited to the macrophage phagosome, where they recognize peptidoglycan, a Gram-positive pathogen component (PMID: 11095740). TLR6 interacts with CD36, following CD36 stimulation by oxLDL or amyloid-beta 42, and forms a heterodimer with TLR4. The trimeric complex is internalized and triggers an inflammatory response.