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TMCO3 Polyklonaler Antikörper

TMCO3 Polyklonal Antikörper für IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31488-1-PBS

Synonyme

C13orf11, FLJ20623, Putative LAG1-interacting protein, Transmembrane and coiled-coil domain-containing protein 3, UNQ2419/PRO4976

Filter:
  • Immunoprecipitation (IP) experiment of HuH-7 cells using TMCO3 Polyclonal antibody (31488-1-AP)

    IP experiment of HuH-7 using 31488-1-AP (same clone as 31488-1-PBS)

    IP result of anti-TMCO3 (IP:31488-1-AP, 4ug; Detection:31488-1-AP 1:1000) with HuH-7 cells lysate 880 ug. This data was developed using the same antibody clone with 31488-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of HepG2 cells using TMCO3 Polyclonal antibody (31488-1-AP)

    IP experiment of HepG2 using 31488-1-AP (same clone as 31488-1-PBS)

    IP result of anti-TMCO3 (IP:31488-1-AP, 4ug; Detection:31488-1-AP 1:1000) with HepG2 cells lysate 1800 ug. This data was developed using the same antibody clone with 31488-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31488-1-PBS bindet in IP, Indirect ELISA TMCO3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TMCO3 fusion protein Ag35012
Vollständiger Name transmembrane and coiled-coil domains 3
Berechnetes Molekulargewicht75 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC068515
Gene symbol TMCO3
Gene ID (NCBI) 55002
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TMCO3, also known as transmembrane and coiled-coil domains 3 or C13orf11, is a protein-coding gene with functional annotation of probable Na+/H+ antiporter. It belongs to the monovalent cation:proton antiporter-2 (CPA2) family according to the Transporter Classification Database (TCDB) (PMID: 33170213). Most CPA2 family members have similar functions and are involved in ion transport (K+, Na+, and H+) in bacteria, archaea, insects, and plants. Upregulated TMCO3 could act as an oncogenic mediator and promote sorafenib resistance in HCC, providing a potential therapeutic target for HCC treatment (PMID: 36304514).