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TMEM164 Polyklonaler Antikörper

TMEM164 Polyklonal Antikörper für IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31625-1-PBS

Synonyme

bB360B22.3, transmembrane protein 164

Filter:
  • Immunohistochemistry (IHC) staining of mouse skeletal muscle tissue using TMEM164 Polyclonal antibody (31625-1-AP)

    IHC staining of mouse skeletal muscle using 31625-1-AP (same clone as 31625-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 31625-1-AP (TMEM164 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31625-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse skeletal muscle tissue using TMEM164 Polyclonal antibody (31625-1-AP)

    IHC staining of mouse skeletal muscle using 31625-1-AP (same clone as 31625-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue slide using 31625-1-AP (TMEM164 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31625-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using TMEM164 Polyclonal antibody (31625-1-AP)

    IF Staining of U2OS using 31625-1-AP (same clone as 31625-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using TMEM164 antibody (31625-1-AP) at dilution of 1:400 and CoraLite®594-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-4). This data was developed using the same antibody clone with 31625-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31625-1-PBS bindet in IHC, IF/ICC, Indirect ELISA TMEM164 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TMEM164 fusion protein Ag34317
Vollständiger Name transmembrane protein 164
GenBank-ZugangsnummerBC085605
Gene symbol TMEM164
Gene ID (NCBI) 84187
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TMEM164 (Transmembrane Protein 164) is a membrane protein with significant roles in various biological processes, including lipid metabolism, neuroprotection, and cancer regulation. In non-small cell lung cancer (NSCLC), TMEM164 promotes ferroptosis by mediating autophagy, leading to the degradation of ferritin, GPX4, and lipid droplets, which facilitates iron accumulation and lipid peroxidation (PMID: 39798196). In neurodegenerative diseases, TMEM164 overexpression via gene therapy shows promise in reducing neurotoxic reactive astrocyte activation and alleviating disease symptoms (PMID: 37679556).