TMEM184B Polyklonaler Antikörper
TMEM184B Polyklonal Antikörper für IHC, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
IHC, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 28031-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
28031-1-PBS bindet in IHC, Indirect ELISA TMEM184B und zeigt Reaktivität mit human
Getestete Reaktivität | human |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Polyklonal |
Typ | Antikörper |
Immunogen | TMEM184B fusion protein Ag27704 |
Vollständiger Name | transmembrane protein 184B |
GenBank-Zugangsnummer | BC015489 |
Gene symbol | TMEM184B |
Gene ID (NCBI) | 25829 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Antigen-Affinitätsreinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Transmembrane protein 184B (TMEM184B) is a seven-pass transmembrane protein highly expressed in the nervous system and is thought to play a role in neuronal excitability, synaptic structure, and expression of key developmental and adult pathways involved in neuronal differentiation (PMID: 27122027; 37730546). TMEM184B may activate the MAP kinase signaling pathway (PMID: 12761501). TMEM184B has also been reported to be necessary for interleukin-31-induced itch, promoting adult somatosensation through developmental Wnt signaling and promotion of proper pruriceptive gene expression (PMID: 34629389).