TMEM231 Polyklonaler Antikörper
TMEM231 Polyklonal Antikörper für IHC, IF/ICC, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Hund
Anwendung
IHC, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 23731-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
23731-1-PBS bindet in IHC, IF/ICC, Indirect ELISA TMEM231 und zeigt Reaktivität mit human, Hund
| Getestete Reaktivität | human, Hund |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | TMEM231 fusion protein Ag20669 |
| Vollständiger Name | hypothetical protein FLJ22167 |
| Berechnetes Molekulargewicht | 345 aa, 39 kDa |
| GenBank-Zugangsnummer | BC010609 |
| Gene symbol | TMEM231 |
| Gene ID (NCBI) | 79583 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Transmembrane protein 231 (TMEM231) encodes a 36 kDa two-pass transmembrane protein that is part of the B9 complex and localizes to the base of the ciliary axoneme at the TZ. TMEM231 was first identified as a causative gene for MKS and participates in the formation of the diffusion barrier between the cilia and plasma membrane (PMID: 34912761, 37736303). Tmem231 mutant mice have developmental defects reminiscent of MKS patients, including corticomedullary kidney cysts, polydactyly and hepatic ductal plate malformation (PMID: 25869670).





