TMEM258 Polyklonaler Antikörper

TMEM258 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31525-1-PBS

Synonyme

C11orf10

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  WB analysis using 31525-1-AP (same clone as 31525-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31525-1-AP (TMEM258 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31525-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse small intestine using 31525-1-AP (same clone as 31525-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue slide using 31525-1-AP (TMEM258 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31525-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 31525-1-AP (same clone as 31525-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31525-1-AP (TMEM258 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31525-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 31525-1-AP (same clone as 31525-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31525-1-AP (TMEM258 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31525-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

31525-1-PBS bindet in WB, IHC, Indirect ELISA TMEM258 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TMEM258 fusion protein Ag35142
• Vollständiger Name: chromosome 11 open reading frame 10
• Beobachtetes Molekulargewicht: 10 and 16 kDa
• GenBank-Zugangsnummer: BC015968
• Gene symbol: C11orf10
• Gene ID (NCBI): 746
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TMEM258, or transmembrane protein 258, is a component of the oligosaccharyltransferase (OST) complex. Research has shown that TMEM258 is involved in controlling ER stress and intestinal inflammation. In particular, it has been identified as a central regulator of intestinal homeostasis. The loss of TMEM258 leads to unresolved ER stress, which can result in apoptosis (PMID: 27974209). The calculated MW is 9 kDa, The observed MW is multiple bands, which may be caused by Glycosylation modification.