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TMEM33 Polyklonaler Antikörper

TMEM33 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30639-1-PBS

Synonyme

Transmembrane protein 33, SHINC-3, SHINC3, Protein DB83, DB83

Filter:
  • Western Blot (WB) analysis of various lysates using TMEM33 Polyclonal antibody (30639-1-AP)

    WB analysis using 30639-1-AP (same clone as 30639-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30639-1-AP (TMEM33 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30639-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30639-1-PBS bindet in WB, Indirect ELISA TMEM33 und zeigt Reaktivität mit Maus, Ratten

Getestete Reaktivität Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TMEM33 fusion protein Ag32368
Vollständiger Name transmembrane protein 33
Berechnetes Molekulargewicht 28 kDa
Beobachtetes Molekulargewicht27-30 kDa
GenBank-ZugangsnummerBC000948
Gene symbol TMEM33
Gene ID (NCBI) 55161
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TMEM33 (transmembrane protein 33), also known as DB83. It is expected to be located in endoplasmic reticulum membrane and nucleus envelope. The protein is widely expressed in prostate cancer and several cancer cell lines (at protein level). And expressed at higher levels in endocrine-resistant breast cancer cells as compared to endocrine-sensitive breast cancer cells. It is also expressed at higher levels in early recurrence breast cancer tissues as compared to non-recurrent breast tumors. The calculated molecular weight of TMEM33 is 28 kDa. It is suggest that TMEM33 has a potency to suppress the membrane-shaping activity of reticulons, thereby regulating the tubular structure of ER (PMID: 25612671).