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TMEM41B Rekombinanter Antikörper

TMEM41B Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242017C11

Kat-Nr. : 84510-4-PBS

Synonyme

Transmembrane protein 41B, KIAA0033, 242017C11

Filter:
  • Western Blot (WB) analysis of various lysates using TMEM41B Recombinant antibody (84510-4-RR)

    WB analysis using 84510-4-RR (same clone as 84510-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84510-4-RR (TMEM41B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84510-4-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84510-4-PBS bindet in WB, Indirect ELISA TMEM41B und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TMEM41B fusion protein Ag30810
Vollständiger Name transmembrane protein 41B
Berechnetes Molekulargewicht32 kDa
Beobachtetes Molekulargewicht25-28 kDa
GenBank-ZugangsnummerBC035034
Gene symbol TMEM41B
Gene ID (NCBI) 440026
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Transmembrane protein 41B (TMEM41B), also known as Stasimon, is a major target of survival motor neuron (SMN)-dependent U12 splicing and has been identified as a protein required for motor circuit function (PMID: 23063131). TMEM41B localizes to the endoplasmic reticulum. It is involved in autophagosome biogenesis and lipid mobilization (PMID: 30126924). TMEM41B has been shown to be essential for mouse embryonic development (PMID: 30352685). Additionally, genome-scale CRISPR knockout screens reveal that TMEM41B is required for infection of flavivirus and coronavirus, including SARS-CoV-2 (PMID: 33052348; 33052332). Alternative splicing results in three transcript variants encoding distinct isoforms.