TMEM45A Polyklonaler Antikörper

TMEM45A Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27534-1-PBS

Synonyme

Dermal papilla-derived protein 7, DERP7, DNA polymerase-transactivated protein 4, DNAPTP4, Transmembrane protein 45A

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  WB analysis using 27534-1-AP (same clone as 27534-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27534-1-AP (TMEM45A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27534-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 27534-1-AP (same clone as 27534-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27534-1-AP (TMEM45A antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27534-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

27534-1-PBS bindet in WB, Indirect ELISA TMEM45A und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TMEM45A fusion protein Ag24392
• Vollständiger Name: transmembrane protein 45A
• Beobachtetes Molekulargewicht: 70-75 kDa
• GenBank-Zugangsnummer: BC040355
• Gene symbol: TMEM45A
• Gene ID (NCBI): 55076
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TMEM45A, also known as DERP7, DNAPTP4, or FLJ10134, is a transmembrane protein belonging to the TMEM family. TMEM45A is highly expressed in keratinocytes and its expression correlates with keratinization, suggesting a role in normal epidermal physiology(PMID: 22954140; PMID: 24689342). TMEM45A promotes cell proliferation, migration, and invasion in glioblastoma cells, favors epithelial-mesenchymal transition (EMT) in colorectal cancer and promotes cell proliferation by favoring the G1/S cell cycle transition in ovarian cancer cells (PMID: 37936608). The predicted molecular weight of TMEM45A is 32 kDa, and 66-98 kDa has been reported in the literature(PMID: 22954140).