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TMEM66 Polyklonaler Antikörper

TMEM66 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 29599-1-PBS

Synonyme

SARAF, FOAP 7, HBV XAg-transactivated protein 3, HBV X-transactivated gene 3 protein, HSPC035

Filter:
  • Immunohistochemistry (IHC) staining of mouse pancreas tissue using TMEM66 Polyclonal antibody (29599-1-AP)

    IHC staining of mouse pancreas using 29599-1-AP (same clone as 29599-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 29599-1-AP (TMEM66 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29599-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse cerebellum tissue using TMEM66 Polyclonal antibody (29599-1-AP)

    IHC staining of mouse cerebellum using 29599-1-AP (same clone as 29599-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 29599-1-AP (TMEM66 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29599-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse pancreas tissue using TMEM66 Polyclonal antibody (29599-1-AP)

    IHC staining of mouse pancreas using 29599-1-AP (same clone as 29599-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue slide using 29599-1-AP (TMEM66 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29599-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

29599-1-PBS bindet in IHC, Indirect ELISA TMEM66 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TMEM66 fusion protein Ag29388
Vollständiger Name transmembrane protein 66
Berechnetes Molekulargewicht 339 aa, 37 kDa
GenBank-ZugangsnummerBC015012
Gene symbol TMEM66
Gene ID (NCBI) 51669
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TMEM66/SOCE-associated regulatory factor (SARAF) is an endoplasmic reticulum (ER)-resident transmembrane protein that promotes SOCE inactivation and prevents Ca2+ overfilling of the cell. TMEM66 plays a key role in shaping cytosolic Ca2+ signals and determining the content of the major intracellular Ca2+ stores, which is probably important in protecting the cell from Ca2+ overfilling (PMID: 37007714). TMEM66 is a highly conserved protein in vertebrates. In mammals, TMEM66 is ubiquitously expressed, but has significantly high transcript levels in the immune and neuronal tissues (PMID: 25469256). Moreover, TMEM66 is an androgen-responsive marker for prostate cancer and mTOR-dependent cardiac growth (PMID:32173353).