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TMPRSS11D Polyklonaler Antikörper

TMPRSS11D Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24634-1-PBS

Synonyme

HAT, MAT, RAT

Filter:
  • Western Blot (WB) analysis of various lysates using TMPRSS11D Polyclonal antibody (24634-1-AP)

    WB analysis using 24634-1-AP (same clone as 24634-1-PBS)

    A-253 cells were subjected to SDS PAGE followed by western blot with 24634-1-AP (TMPRSS11D antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24634-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

24634-1-PBS bindet in WB, Indirect ELISA TMPRSS11D und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TMPRSS11D fusion protein Ag17841
Vollständiger Name transmembrane protease, serine 11D
Berechnetes Molekulargewicht 418 aa, 46 kDa
Beobachtetes Molekulargewicht46 kDa
GenBank-ZugangsnummerBC125195
Gene symbol TMPRSS11D
Gene ID (NCBI) 9407
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TMPRSS11D, also known as human airway trypsin-like protease (HAT), is a type II transmembrane serine protease that plays a crucial role in various biological processes, including viral infections and cancer progression. This protease is expressed in the epithelial cells of the respiratory tract and has been implicated in the activation of several viruses, such as SARS-CoV-2. In addition to its role in viral infections, TMPRSS11D has also been involved in cancer progression. High expression levels of TMPRSS11D have been associated with poor overall survival in non-small cell lung cancer. This suggests that TMPRSS11D may contribute to tumor growth and metastasis, making it a potential biomarker and therapeutic target in oncology. (PMID: 28086212, PMID: 40348740)