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TNC/Tenascin-C Rekombinanter Antikörper

TNC/Tenascin-C Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242866C6

Kat-Nr. : 85821-1-PBS

Synonyme

Hexabrachion, Hxb, Tenascin, Tenascin-C, TN

Filter:
  • Western Blot (WB) analysis of mouse colon tissue using TNC/Tenascin-C Recombinant antibody (85821-1-RR)

    WB analysis of mouse colon using 85821-1-RR (same clone as 85821-1-PBS)

    mouse colon tissue were subjected to SDS PAGE followed by western blot with 85821-1-RR (Tnc antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85821-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse thymus tissue using TNC/Tenascin-C Recombinant antibody (85821-1-RR)

    WB analysis of mouse thymus using 85821-1-RR (same clone as 85821-1-PBS)

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with 85821-1-RR (Tnc antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85821-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85821-1-PBS bindet in WB, Indirect ELISA TNC/Tenascin-C und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TNC/Tenascin-C fusion protein Eg2849
Vollständiger Name tenascin C
Berechnetes Molekulargewicht232 kDa
Beobachtetes Molekulargewicht210-230 kDa
GenBank-ZugangsnummerN/A
Gene symbol Tnc
Gene ID (NCBI) 21923
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tenascin-C (TNC) is a large hexameric extracellular matrix glycoprotein of the tenascin family (PMID: 21818551). It is a multimodular protein containing multiple epidermal growth factor (EGF)-like repeats and fibronectin type III (FN III) domains (PMID: 1719530). Tenascin-C is highly expressed during embryonic development, particularly in the developing central nervous system, around motile cells and at epithelial-mesenchymal interaction sites (PMID: 25738825). In adult tissues, the expression and the distribution of TNC are typically limited under normal physiological conditions. It is upregulated during injury, inflammation, regeneration, and cancer (PMID: 7694605; 25120494). Tenascin-C is a diverse protein that can produce different functions including regulating cell adhesion, migration and proliferation.