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TNF beta Rekombinanter Antikörper

TNF beta Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC (Intra)

Konjugation

Unkonjugiert

CloneNo.

240393C3

Kat-Nr. : 98056-1-PBS

Synonyme

LTA, TNF β, Lymphotoxin-alpha, Lymphotoxin alpha, LT alpha

Filter:
  • Flow cytometry (FC) experiment of human PBMCs using Anti-Human TNF beta Rabbit Recombinant Antibody (98056-1-RR)

    FC experiment of human PBMCs using 98056-1-RR (same clone as 98056-1-PBS)

    1x10^6 untreated or anti-CD3/CD28 treated human PBMCs were intracellularly stained with 0.25 ug Anti-Human TNF beta Rabbit Recombinant Antibody (98056-1-RR, Clone: 240393C3) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG. Cells were then stained with APC Anti-Human CD3. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98056-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98056-1-RR

    Affinity and Kinetic Characterization of 98056-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98056-1-RR against Human TNF Beta were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

98056-1-PBS bindet in FC (Intra) TNF beta und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Fusionsprotein
Vollständiger Name lymphotoxin alpha (TNF superfamily, member 1)
Berechnetes Molekulargewicht 205 aa, 22 kDa
GenBank-ZugangsnummerBC034729
Gene symbol TNF beta
Gene ID (NCBI) 4049
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C.

Hintergrundinformationen

TNF beta also known as lymphotoxin alpha (LTA), is a member of the tumor necrosis factor family, and is a cytokine produced by lymphocytes. TNF Beta is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. TNF Beta also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.