• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

TNFAIP8 Monoklonaler Antikörper

TNFAIP8 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3D2F7

Kat-Nr. : 67737-1-PBS

Synonyme

GG2 1, MDC 3.13, NDED, SCC S2, SCCS2, TNF alpha induced protein 8, TNF induced protein GG2 1, TNFAIP8

Filter:
  • Western Blot (WB) analysis of various lysates using TNFAIP8 Monoclonal antibody (67737-1-Ig)

    WB analysis using 67737-1-Ig (same clone as 67737-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67737-1-Ig (TNFAIP8 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67737-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67737-1-PBS bindet in WB, Indirect ELISA TNFAIP8 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen TNFAIP8 fusion protein Ag8805
Vollständiger Name tumor necrosis factor, alpha-induced protein 8
Berechnetes Molekulargewicht 198 aa, 23 kDa
Beobachtetes Molekulargewicht19-21 kDa
GenBank-ZugangsnummerBC007014
Gene symbol TNFAIP8
Gene ID (NCBI) 25816
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TNFAIP8 (tumor necrosis factor, alpha-induced protein 8), also called SCC-S2/GG2-1/NDED, is associated with enhanced cell survival and inhibition of apoptosis. The induction of TNFAIP8 by TNF depends on the activation of NFκB. TNFAIP8 suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. TNFAIP8 is expressed in adult spleen, lymph node, thymus, thyroid, bone marrow, and placenta, and in fetal liver, lung, and kidney at high levels, also expressed in various tumor tissues and all cancer cell lines tested.