TNFAIP8L3 Polyklonaler Antikörper

TNFAIP8L3 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(2)

Kat-Nr. : 20693-1-AP

Synonyme

TIPE3, TNFAIP8 like protein 3, TNFAIP8L3

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  WB analysis using 20693-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 20693-1-AP (TNFAIP8L3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: A549-Zellen, Jurkat-Zellen, MCF-7-Zellen, Mausmilzgewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below
• IHC: See 1 publications below

Produktinformation

20693-1-AP bindet in WB, IHC, ELISA TNFAIP8L3 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: tumor necrosis factor, alpha-induced protein 8-like 3
• Berechnetes Molekulargewicht: 33 kDa
• Beobachtetes Molekulargewicht: 37 kDa
• GenBank-Zugangsnummer: NM_207381
• Gene symbol: TNFAIP8L3
• Gene ID (NCBI): 388121
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TNFAIP8L3 (tumor necrosis factor alpha-induced protein 8-like protein 3), also known as TIPE3, is a member of the TNFAIP8 family which also include TNFAIP8 (TIPE), TNFAIP8L1 (TIPE1) and TNFAIP8L2 (TIPE2) (PMID: 18455983; 21924498). TNFAIP8L3 is a transfer protein for phosphoinositide second messengers. It is markedly upregulated in human cancer cells and may represent a therapeutic target for treating malignant diseases (PMID: 25242044). This antibody is specific to TNFAIP8L3.

Publikationen

Species	Application	Title
human	WB	Hum Mol Genet; CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.; Authors - Xiaoping Huang
human	IHC	Cell Death Discov; TIPE3 promotes drug resistance in colorectal cancer by enhancing autophagy via the USP19/Beclin1 pathway; Authors - Chun Chen