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TNFRSF13B/CD267 Rekombinanter Antikörper

TNFRSF13B/CD267 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241317C9

Kat-Nr. : 84266-3-PBS

Synonyme

CD267, TNFRSF13B, 241317C9, CVID, TACI

Filter:
  • Western Blot (WB) analysis of various lysates using TNFRSF13B/CD267 Recombinant antibody (84266-3-RR)

    WB analysis using 84266-3-RR (same clone as 84266-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84266-3-RR (TNFRSF13B/CD267 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84266-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84266-3-PBS bindet in WB, Indirect ELISA TNFRSF13B/CD267 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name tumor necrosis factor receptor superfamily, member 13B
Berechnetes Molekulargewicht 293 aa, 32 kDa
Beobachtetes Molekulargewicht32 kDa
GenBank-ZugangsnummerBC109392
Gene symbol TNFRSF13B/CD267
Gene ID (NCBI) 23495
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.