TNFRSF13B/CD267 Rekombinanter Antikörper

TNFRSF13B/CD267 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250265B1

Kat-Nr. : 98439-2-RR

Synonyme

CD267, Taci, Tnfrsf13b, Transmembrane activator and CAML interactor, Tumor necrosis factor receptor superfamily member 13B

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  FC experiment of mouse splenocytes using 98439-2-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse TACI/TNFRSF13B Rabbit RecAb (98439-2-RR, Clone: 250265B1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Mouse CD19. Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 98439-2-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse TACI/TNFRSF13B Rabbit RecAb (98439-2-RR, Clone: 250265B1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Maus-Splenozyten

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98439-2-RR bindet in FC TNFRSF13B/CD267 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TNFRSF13B/CD267 fusion protein Eg1814
• Vollständiger Name: tumor necrosis factor receptor superfamily, member 13b
• Berechnetes Molekulargewicht: 27 kDa
• GenBank-Zugangsnummer: NM_021349.1
• Gene symbol: Tnfrsf13b
• Gene ID (NCBI): 57916
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.