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CD268/BAFF-R Monoklonaler Antikörper

CD268/BAFF-R Monoklonal Antikörper für Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgM

Getestete Reaktivität

human

Anwendung

Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2D9D11

Kat-Nr. : 60763-3-PBS

Synonyme

TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor

Filter:
  • Cytometric bead array standard curve of MP51091-2

    Cytometric bead array standard curve of MP51091-2

    Cytometric bead array standard curve of MP51091-2, TNFRSF13C Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60763-1-PBS. Detection antibody: 60763-3-PBS. Standard:Ag18512. Range: 0.098-100 ng/mL.

  • Cytometric bead array standard curve of MP51091-4

    Cytometric bead array standard curve of MP51091-4

    Cytometric bead array standard curve of MP51091-4, TNFRSF13C Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60763-2-PBS. Detection antibody: 60763-3-PBS. Standard:Ag18512. Range: 0.781-100 ng/mL.

Geprüfte Anwendungen

Produktinformation

60763-3-PBS bindet in Cytometric bead array, Indirect ELISA CD268/BAFF-R und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgM
Klonalität Monoklonal
Typ Antikörper
Immunogen CD268/BAFF-R fusion protein Ag18512
Vollständiger Name tumor necrosis factor receptor superfamily, member 13C
Berechnetes Molekulargewicht 184 aa, 19 kDa
GenBank-ZugangsnummerBC105123
Gene symbol TNFRSF13C
Gene ID (NCBI) 115650
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Caprylsäure/Ammoniumsulfat-Präzipitation
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).