• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

CD268/BAFF-R Monoklonaler Antikörper

CD268/BAFF-R Monoklonal Antikörper für Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgM

Getestete Reaktivität

human

Anwendung

Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2E8E12

Kat-Nr. : 60763-4-PBS

Synonyme

TNFRSF13C, B-cell-activating factor receptor, BAFF-R, BAFFR, BAFF receptor

Filter:
  • Cytometric bead array standard curve of MP51091-3

    Cytometric bead array standard curve of MP51091-3

    Cytometric bead array standard curve of MP51091-3, TNFRSF13C Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60763-2-PBS. Detection antibody: 60763-4-PBS. Standard:Ag18512. Range: 0.391-100 ng/mL.

Geprüfte Anwendungen

Produktinformation

60763-4-PBS bindet in Cytometric bead array, Indirect ELISA CD268/BAFF-R und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgM
Klonalität Monoklonal
Typ Antikörper
Immunogen CD268/BAFF-R fusion protein Ag18512
Vollständiger Name tumor necrosis factor receptor superfamily, member 13C
Berechnetes Molekulargewicht 184 aa, 19 kDa
GenBank-ZugangsnummerBC105123
Gene symbol TNFRSF13C
Gene ID (NCBI) 115650
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Caprylsäure/Ammoniumsulfat-Präzipitation
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).