TNFRSF9/CD137 Rekombinanter Antikörper

TNFRSF9/CD137 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

PE Fluorescent Dye

CloneNo.

241647E11

Kat-Nr. : PE-FcA98182

Synonyme

4-1BB, 4-1BB ligand receptor, CD137, Ila, Ly63

---

• 

  FC experiment of mouse splenocytes using PE-FcA98182

  1x10^6 untreated or Con A-treated mouse splenocytes were surface stained with APC Anti-Mouse CD25/IL-2RA and 0.1 ug PE Anti-Mouse TNFRSF9/CD137 Rabbit RecAb (PE-FcA98182, Clone: 241647E11). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using PE-FcA98182

  1x10^6 Con A-treated mouse splenocytes were surface stained with 0.1 ug PE Anti-Mouse TNFRSF9/CD137 Rabbit RecAb (PE-FcA98182, Clone: 241647E11) (red) or 0.1 ug PE Rabbit IgG Isotype Control RecAb (PE-FcA98136, Clone: 240953C9) (blue). 1x10^6 untreated mouse splenocytes were surface stained with 0.1 ug PE Anti-Mouse TNFRSF9/CD137 Rabbit RecAb (PE-FcA98182, Clone: 241647E11) (black, dashed). Cells were not fixed.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: Con A treated mouse splenocytes

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

PE-FcA98182 bindet in FC TNFRSF9/CD137 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TNFRSF9/CD137 fusion protein Eg1627
• Vollständiger Name: tumor necrosis factor receptor superfamily, member 9
• Berechnetes Molekulargewicht: 28 kDa
• GenBank-Zugangsnummer: NM_001077509.1
• Gene symbol: Tnfrsf9
• Gene ID (NCBI): 21942
• Konjugation: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

CD137, also known as TNFRSF9 or 4-1BB, is an inducible T cell surface receptor that belongs to the tumor necrosis factor receptor superfamily. CD137 is a transmembrane protein expressed on the surface of activated T-cells. In addition, activation-dependent expression of CD137 has also been found in B lymphocytes, monocytes, and diverse nonlymphoid cell types. CD137 provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development of CD8 cytotoxic T cells and anti-tumor immunity. (PMID: 9826581; 23696891)