TOM70 Rekombinanter Antikörper
TOM70 Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
251874H2
Kat-Nr. : 86840-3-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
86840-3-PBS bindet in WB, Indirect ELISA TOM70 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | TOM70 fusion protein Ag6027 |
| Vollständiger Name | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) |
| Berechnetes Molekulargewicht | 67 kDa |
| Beobachtetes Molekulargewicht | 70 kDa |
| GenBank-Zugangsnummer | BC052994 |
| Gene symbol | TOM70 |
| Gene ID (NCBI) | 9868 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
TOMM70A (or TOM70) is a mitochondrial import receptor responsible for the import of cytosol synthesized precursor proteins into the mitochondria. Tom70 is a member of the tetratricopeptide repeat (TPR) co-chaperone family and contains a conserved TPR clamp domain for interaction with Hsc70 and Hsp90. Recently overexpression of TOM70 has been linked to chemoresistance to drugs in breast cancer cell lines. It is also believed that Tom70 is significantly associated with breast cancer relapse and may predict the recurrence of ovarian cancer.

