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TOR1B Polyklonaler Antikörper

TOR1B Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21945-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using TOR1B Polyclonal antibody (21945-1-AP)

    WB analysis using 21945-1-AP (same clone as 21945-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21945-1-AP (TOR1B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21945-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

21945-1-PBS bindet in WB, Indirect ELISA TOR1B und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TOR1B fusion protein Ag16641
Vollständiger Name torsin family 1, member B (torsin B)
Berechnetes Molekulargewicht 336 aa, 38 kDa
Beobachtetes Molekulargewicht 34 kDa
GenBank-ZugangsnummerBC015578
Gene symbol TOR1B
Gene ID (NCBI) 27348
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Torsin A is 1 of 4 predicted mammalian torsin ATPases associated with assorted cellular activities (AAA+) proteins (PMID: 20015956). TOR1B (torsin family 1 member B), also called TorsinB (TorB), is similar to TorsinA at the sequence level. TorsinA and TorsinB are both ubiquitously expressed in all cell types though TorsinA is more highly expressed in neurons. TorsinA and TorsinB may be somewhat functionally redundant, with TorsinA being more important in neuronal cells and TorsinB being more important in other tissues (PMID: 24275647). TOR1B serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins,and plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity (PMID: 24275647; 23569223).