TOR1B Rekombinanter Antikörper

TOR1B Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241574A7

Kat-Nr. : 84267-3-PBS

Synonyme

241574A7, DQ1, Torsin 1B, Torsin family 1 member B

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  WB analysis using 84267-3-RR (same clone as 84267-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84267-3-RR (TOR1B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84267-3-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP01175-1

  Cytometric bead array standard curve of MP01175-1, TOR1B Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84267-1-PBS. Detection antibody: 84267-3-PBS. Standard: Ag16641. Range: 0.313-40 ng/mL.

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  Cytometric bead array standard curve of MP01175-2

  Cytometric bead array standard curve of MP01175-2, TOR1B Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84267-2-PBS. Detection antibody: 84267-3-PBS. Standard: Ag16641. Range: 0.313-40 ng/mL.

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  Affinity and Kinetic Characterization of 84267-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84267-3-RR against Human TOR1B were performed. The affinity constant is 14.5 nM.

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Geprüfte Anwendungen

Produktinformation

84267-3-PBS bindet in WB, Cytometric bead array, Indirect ELISA TOR1B und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TOR1B fusion protein Ag16641
• Vollständiger Name: torsin family 1, member B (torsin B)
• Berechnetes Molekulargewicht: 336 aa, 38 kDa
• Beobachtetes Molekulargewicht: 35 kDa
• GenBank-Zugangsnummer: BC015578
• Gene symbol: TOR1B
• Gene ID (NCBI): 27348
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Torsin A is 1 of 4 predicted mammalian torsin ATPases associated with assorted cellular activities (AAA+) proteins (PMID: 20015956). TOR1B (torsin family 1 member B), also called TorsinB (TorB), is similar to TorsinA at the sequence level. TorsinA and TorsinB are both ubiquitously expressed in all cell types though TorsinA is more highly expressed in neurons. TorsinA and TorsinB may be somewhat functionally redundant, with TorsinA being more important in neuronal cells and TorsinB being more important in other tissues (PMID: 24275647). TOR1B serve as a molecular chaperone assisting in the proper folding of secreted and/or membrane proteins,and plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity (PMID: 24275647; 23569223).