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TPH1 Polyklonaler Antikörper

TPH1 Polyklonal Antikörper für WB,ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB,ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20879-1-AP

Synonyme

TPH, TPH1, TPRH, TRPH, Tryptophan 5 hydroxylase 1, Tryptophan 5 monooxygenase 1, tryptophan hydroxylase 1

Galerie der Validierungsdaten

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  • Western Blot (WB) analysis of SH-SY5Y cells using TPH1 Polyclonal antibody (20879-1-AP)

    WB analysis of SH-SY5Y using 20879-1-AP

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 20879-1-AP (TPH1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

Geprüfte Anwendungen

Erfolgreiche Detektion in WBSH-SY5Y-Zellen

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

20879-1-AP bindet in WB,ELISA TPH1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TPH1 fusion protein Ag14978
Vollständiger Name tryptophan hydroxylase 1
Berechnetes Molekulargewicht 466 aa, 53 kDa
Beobachtetes Molekulargewicht 51 kDa
GenBank-ZugangsnummerBC106739
Gene symbol TPH1
Gene ID (NCBI) 7166
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tryptophan hydroxylase 1(TPH1) catalyzes the rate-limiting step in the synthesis of serotonin in the periphery. Recently, it has been shown that expression of the tryptophan hydroxylase 1 gene is increased in lungs and pulmonary endothelial cells from patients with idiopathic pulmonary arterial hypertension. It catalyzes the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. The protein has low expression.