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TRAIP Rekombinanter Antikörper

TRAIP Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251370C8

Kat-Nr. : 86808-1-PBS

Synonyme

TRIP, EC:2.3.2.27, RING finger protein 206, RNF206, TRAF interacting protein

Filter:
  • Western Blot (WB) analysis of various lysates using TRAIP Recombinant monoclonal antibody (86808-1-RR)

    WB analysis using 86808-1-RR (same clone as 86808-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86808-1-RR (TRAIP antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86808-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86808-1-RR

    Affinity and Kinetic Characterization of 86808-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86808-1-RR against Human TRAIP were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

86808-1-PBS bindet in WB, Indirect ELISA TRAIP und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TRAIP fusion protein Ag0491
Vollständiger Name TRAF interacting protein
Berechnetes Molekulargewicht 53 kDa
Beobachtetes Molekulargewicht 53 kDa
GenBank-ZugangsnummerBC000310
Gene symbol TRAIP
Gene ID (NCBI) 10293
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

E3 ubiquitin-protein ligase TRAIP (TRAIP) is also named RING finger protein 206 (RNF206) and TRAF-interacting protein (TRIP). TRAIP, an E3 ligase containing a RING domain, has emerged as a significant contributor to maintaining genome integrity and TRAIP inhibits proliferation and migration of BLCA cells (PMID: 38123820). TRAIP helps replisomes overcome DNA interstrand crosslinks and DNA-protein crosslinks, whereas in mitosis it triggers disassembly of all replisomes that remain on chromatin (PMID: 33317933, PMID: 30842657).