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TRANK1 Polyklonaler Antikörper

TRANK1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27583-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using TRANK1 Polyclonal antibody (27583-1-AP)

    WB analysis using 27583-1-AP (same clone as 27583-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27583-1-AP (TRANK1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27583-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27583-1-PBS bindet in WB, Indirect ELISA TRANK1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TRANK1 fusion protein Ag26206
Vollständiger Name lupus brain antigen 1
Berechnetes Molekulargewicht 336 kDa
Beobachtetes Molekulargewicht~330 kDa
GenBank-ZugangsnummerNM_014831
Gene symbol LBA1
Gene ID (NCBI) 9881
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Etratricopeptide repeat and ankyrin repeat containing 1 (TRANK1), has been confirmed as the susceptibility gene for BD (bipolar disorder). An integrated analysis of mRNA co-expression networks revealed that genes highly correlated with TRANK1 were significantly involved in the biological processes related to synaptic plasticity, dendritic spine, axon guidance and circadian rhythm. In addition, TRANK1 rs71947856 variant was associated with circadian regulation and Kleine-Levin syndrome, which is a rare disease characterized by severe episodic hypersomnia, with cognitive impairment and apathy or disinhibition.(PMID: 34014031)