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TRBP Monoklonaler Antikörper

TRBP Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1C9A10

Kat-Nr. : 66792-1-PBS

Synonyme

LOQS, TAR RNA binding protein 2, TARBP2, TRBP, TRBP1, TRBP2

Filter:
  • Western Blot (WB) analysis of various lysates using TRBP Monoclonal antibody (66792-1-Ig)

    WB analysis using 66792-1-Ig (same clone as 66792-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66792-1-Ig (TRBP antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66792-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using TRBP Monoclonal antibody (66792-1-Ig)

    IHC staining of human breast cancer using 66792-1-Ig (same clone as 66792-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66792-1-Ig (TRBP antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66792-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human breast cancer tissue using TRBP Monoclonal antibody (66792-1-Ig)

    IHC staining of human breast cancer using 66792-1-Ig (same clone as 66792-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66792-1-Ig (TRBP antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66792-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66792-1-PBS bindet in WB, IHC, Indirect ELISA TRBP und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen TRBP fusion protein Ag8269
Vollständiger Name TAR (HIV-1) RNA binding protein 2
Berechnetes Molekulargewicht 39 kDa
Beobachtetes Molekulargewicht 43-46 kDa
GenBank-ZugangsnummerBC005860
Gene symbol TRBP
Gene ID (NCBI) 6895
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC). Within the complex, TARBP2 and DICER1 are required to process precursor miRNAs (pre-miRNA) to mature miRNA and then load them onto EIF2C2/AGO2. It may has a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Otherwise, it binds to the HIV-1 TAR RNA that is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. The endogenous TRBP that was present in HEK293 cells, with apparent molecular masses of 43-46 kDa, are expressed in human cells. (PMID: 16142218)