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TREK1/KCNK2 Polyklonaler Antikörper

TREK1/KCNK2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26807-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using TREK1/KCNK2 Polyclonal antibody (26807-1-AP)

    WB analysis using 26807-1-AP (same clone as 26807-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26807-1-AP (TREK1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26807-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

26807-1-PBS bindet in WB, Indirect ELISA TREK1/KCNK2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TREK1/KCNK2 fusion protein Ag25209
Vollständiger Name potassium channel, subfamily K, member 2
Berechnetes Molekulargewicht 411 aa, 46 kDa
Beobachtetes Molekulargewicht40-50 kDa
GenBank-ZugangsnummerBC101693
Gene symbol TREK1
Gene ID (NCBI) 3776
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The tandem of pore domains in a weak inward rectifying K+ channel (TWIK1, K2P1.1, or KCNK1) and TWIK-related K+channel 1 (TREK1, K2P 2.1, or KCNK2) are members of the two pore domain potassium (K2P) channel family, consisting of 15 channels that regulate the stabilization of resting membrane potential and cellular excitability by wielding background K+ leakage currents (PMID:12580339). TREK1/KCNK2 is sensitive to a wide range of physical and chemical cues. Its main role is to maintain the resting potential of the cell and whilst highly expressed in the nervous system, TREK1/KCNK2 is also expressed in the kidney, heart, lung and smooth muscle cells (PMID:31031627).