TREM-1/CD354 Rekombinanter Antikörper

TREM-1/CD354 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

PE Fluorescent Dye

CloneNo.

241279D10

Kat-Nr. : PE-FcA98154

Synonyme

TREM1, CD354, TREM 1

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  FC experiment of human peripheral blood leukocytes using PE-FcA98154

  1x10^6 human peripheral blood leukocytes were surface stained with CoraLite® Plus 405 Anti-Human CD16, and 5 ul PE Anti-Human TREM-1/CD354 Rabbit RecAb (PE-FcA98154, Clone:241279D10) or PE Rabbit IgG Isotype Control RecAb (PE-FcA98136, Clone: 240953C9). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: human peripheral blood leukocytes

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

PE-FcA98154 bindet in FC TREM-1/CD354 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TREM-1/CD354 fusion protein Eg1438
• Vollständiger Name: triggering receptor expressed on myeloid cells 1
• Berechnetes Molekulargewicht: 26kDa
• GenBank-Zugangsnummer: NM_018643.5
• Gene symbol: TREM1
• Gene ID (NCBI): 54210
• Konjugation: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

Triggering receptor expressed on myeloid cells 1 (TREM-1, also known as CD354) is a member of the immunoglobulin superfamily, which is expressed on neutrophils and monocytes. TREM1 plays a role in the innate immune system. TREM1 amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers.