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TRH Polyklonaler Antikörper

TRH Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25332-1-PBS

Synonyme

Prothyroliberin, Pro-thyrotropin-releasing hormone, Protirelin, Thyrotropin-releasing hormone, TRF

Filter:
  • Western Blot (WB) analysis of various lysates using TRH Polyclonal antibody (25332-1-AP)

    WB analysis using 25332-1-AP (same clone as 25332-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25332-1-AP (TRH antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25332-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using TRH Polyclonal antibody (25332-1-AP)

    IHC staining of human brain using 25332-1-AP (same clone as 25332-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 25332-1-AP (TRH antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25332-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25332-1-PBS bindet in WB, IHC, Indirect ELISA TRH und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TRH fusion protein Ag12623
Vollständiger Name thyrotropin-releasing hormone
Berechnetes Molekulargewicht 242 aa, 27 kDa
Beobachtetes Molekulargewicht27-33 kDa
GenBank-ZugangsnummerBC074889
Gene symbol TRH
Gene ID (NCBI) 7200
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TRH, Thyrotropin-releasing hormone, as a component of the hypothalamic-pituitary-thyroid axis, controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as modulator of hair growth and promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its termination (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes. TRH is expressed in hypothalamus and the hair follicle epithelium (PMID: 19825978).