TRIM38 Polyklonaler Antikörper

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• KD/KO Validated

TRIM38 Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13405-1-PBS

Synonyme

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  WB analysis of human liver using 13405-1-AP (same clone as 13405-1-PBS)

  human liver tissue were subjected to SDS PAGE followed by western blot with 13405-1-AP (TRIM38 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human colon using 13405-1-AP (same clone as 13405-1-PBS)

  human colon tissue were subjected to SDS PAGE followed by western blot with 13405-1-AP (TRIM38 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 13405-1-AP (same clone as 13405-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 13405-1-AP (TRIM38 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 13405-1-AP (same clone as 13405-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 13405-1-AP (same clone as 13405-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 13405-1-AP (same clone as 13405-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 13405-1-AP (same clone as 13405-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 13405-1-AP (TRIM38 antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

• 

  IF Staining of L02 using 13405-1-AP (same clone as 13405-1-PBS)

  Immunofluorescent analysis of (-20℃ Ethanol) fixed L02 cells using 13405-1-AP (TRIM38 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13405-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

13405-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA TRIM38 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TRIM38 fusion protein Ag3840
• Vollständiger Name: tripartite motif-containing 38
• Berechnetes Molekulargewicht: 465 aa, 53 kDa
• Beobachtetes Molekulargewicht: 53 kDa
• GenBank-Zugangsnummer: BC026930
• Gene symbol: TRIM38
• Gene ID (NCBI): 10475
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The proinflammatory cytokines TNFα and IL-1β play central roles in many diseases, including infectious diseases, autoimmunity, and cancers. TRIM38 belongs to the TRIM protein family that is involved in various biological processes, including cell proliferation and apoptosis, innate immunity, and inflammatory response. It has been shown that TRIM38 acts as a suppressor in TOLL-like receptor (TLR)-mediated IFN-β induction by promoting degradation of TRAF6 and NAP1 through the ubiquitinproteasome system. (PMID:24434549)