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TRIM58 Polyklonaler Antikörper

TRIM58 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28725-1-PBS

Synonyme

BIA2, Protein BIA2, TRIM, tripartite motif containing 58

Filter:
  • Western Blot (WB) analysis of various lysates using TRIM58 Polyclonal antibody (28725-1-AP)

    WB analysis using 28725-1-AP (same clone as 28725-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28725-1-AP (TRIM58 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28725-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of PC-3 cells using TRIM58 Polyclonal antibody (28725-1-AP)

    WB analysis of PC-3 using 28725-1-AP (same clone as 28725-1-PBS)

    WB result of TRIM58 antibody (28725-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-TRIM58 transfected PC-3 cells. This data was developed using the same antibody clone with 28725-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28725-1-PBS bindet in WB, Indirect ELISA TRIM58 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TRIM58 fusion protein Ag30014
Vollständiger Name tripartite motif-containing 58
Berechnetes Molekulargewicht 55 kDa
Beobachtetes Molekulargewicht 55 kDa
GenBank-ZugangsnummerNM_015431
Gene symbol TRIM58
Gene ID (NCBI) 25893
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TRIM58 (Tripartite motif-containing protein 58) is an E3 ubiquitin ligase induced during late erythropoiesis. It can directly bind and ubiquitinate the intermediate chain of the microtubule motor dynein (DYNC1LI1/DYNC1LI2), stimulating the degradation of the dynein holoprotein complex. May participate in the erythroblast enucleation process through regulation of nuclear polarization (PMID: 25241935).