TRIM63 Rekombinanter Antikörper
TRIM63 Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
242055A4
Kat-Nr. : 82345-4-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
82345-4-PBS bindet in WB, Indirect ELISA TRIM63 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | Peptid |
| Vollständiger Name | tripartite motif-containing 63 |
| Berechnetes Molekulargewicht | 40 kDa |
| Beobachtetes Molekulargewicht | 40 kDa |
| GenBank-Zugangsnummer | NM_032588 |
| Gene symbol | TRIM63 |
| Gene ID (NCBI) | 84676 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein A purfication |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
TRIM63, also named as IRF, MURF1, RNF28 and SMRZ, is E3 ubiquitin ligase. It is regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. TRIM63 may play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. It may regulate the organization of myofibrils through TTN in muscle cells. TRIM63 is in muscle-specific expression.

