• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

TRMU Rekombinanter Antikörper

TRMU Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250434A4

Kat-Nr. : 86095-1-PBS

Synonyme

EC:2.8.1.14, Mitochondrial tRNA-specific 2-thiouridylase 1, MTO2, MTO2 homolog, MTU1

Filter:
  • Western Blot (WB) analysis of various lysates using TRMU Recombinant antibody (86095-1-RR)

    WB analysis using 86095-1-RR (same clone as 86095-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86095-1-RR (TRMU antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86095-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86095-1-RR

    Affinity and Kinetic Characterization of 86095-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86095-1-RR against Human TRMU were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

86095-1-PBS bindet in WB, Indirect ELISA TRMU und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TRMU fusion protein Ag21930
Vollständiger Name tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
Berechnetes Molekulargewicht 421 aa, 48 kDa
Beobachtetes Molekulargewicht 45 kDa
GenBank-ZugangsnummerBC027991
Gene symbol TRNT1
Gene ID (NCBI) 55687
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TRMU (tRNA m5C methyltransferase) is a mitochondrial protein involved in the modification of mitochondrial tRNA. Specifically, it catalyzes the formation of 5-methylcytidine at position 34 (m5C34) in the anticodon stem-loop of mitochondrial tRNAs, which is crucial for maintaining the stability and function of these tRNAs. TRMU is a nuclear-encoded protein located in the mitochondrial matrix. It plays a vital role in mitochondrial translation and oxidative phosphorylation.TRMU is associated with several genetic disorders. Mutations in the TRMU gene can cause mitochondrial diseases, such as infantile hepatic failure syndrome. (PMID:23625533)