TRPC3 Rekombinanter Antikörper

TRPC3 Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241075H3

Kat-Nr. : 84019-5-PBS

Synonyme

Transient receptor protein 3, Short transient receptor potential channel 3, hTrp-3, hTrp3, hTrp 3

---

• 

  WB analysis using 84019-5-RR (same clone as 84019-5-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84019-5-RR (TRPC3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84019-5-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 84019-5-RR (same clone as 84019-5-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 84019-5-RR (TRPC3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84019-5-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP00972-1

  Cytometric bead array standard curve of MP00972-1, TRPC3 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84019-5-PBS. Detection antibody: 84019-4-PBS. Standard: Ag13024. Range: 0.781-100 ng/mL.

---

Geprüfte Anwendungen

Produktinformation

84019-5-PBS bindet in WB, Cytometric bead array, Indirect ELISA TRPC3 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TRPC3 fusion protein Ag13024
• Vollständiger Name: transient receptor potential cation channel, subfamily C, member 3
• Berechnetes Molekulargewicht: 848 aa, 97 kDa
• Beobachtetes Molekulargewicht: 105 kDa, 97 kDa
• GenBank-Zugangsnummer: BC093682
• Gene symbol: TRPC3
• Gene ID (NCBI): 7222
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TRPC3 (Short transient receptor potential channel 3), also known as TRP3. It is expected to be located in the cell membrane, which is expressed predominantly in brain and at much lower levels in ovary, colon, small intestine, lung, prostate, placenta and testis. TRPC3 is one of the classical members of the mammalian transient receptor potential (TRP) superfamily of ion channels. TRPC3 is a molecule with intriguing sensory features including the direct recognition of and activation by diacylglycerols (DAG). Although TRPC3 channels are ubiquitously expressed, they appear to control functions of the cardiovascular system and the brain in a highly specific manner. Moreover, a role of TRPC3 in immunity, cancer, and tissue remodeling has been proposed, generating much interest in TRPC3 as a target for pharmacological intervention. The molecular weight of TRPC3 is 105 kDa, and it can recognize another isoform. (PMID: 30037143)