TRPC4AP Monoklonaler Antikörper

TRPC4AP Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG3

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2C10B1

Kat-Nr. : 66138-1-PBS

Synonyme

C20orf188, Protein TAP1, Protein TRUSS, Trp4 associated protein, Trpc4 associated protein, TRPC4AP, TRRP4AP, TRUSS

---

• 

  WB analysis of human brain using 66138-1-Ig (same clone as 66138-1-PBS)

  human brain tissue were subjected to SDS PAGE followed by western blot with 66138-1-Ig (TRPC4AP antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66138-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human heart using 66138-1-Ig (same clone as 66138-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 66138-1-Ig (TRPC4AP antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66138-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 66138-1-Ig (same clone as 66138-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver using 66138-1-Ig(TRPC4AP antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66138-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 66138-1-Ig (same clone as 66138-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 66138-1-Ig (TRPC4AP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 66138-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 66138-1-Ig (same clone as 66138-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver using 66138-1-Ig(TRPC4AP antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66138-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 66138-1-Ig (same clone as 66138-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer slide using 66138-1-Ig (TRPC4AP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 66138-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

66138-1-PBS bindet in WB, IHC, Indirect ELISA TRPC4AP und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG3
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: TRPC4AP fusion protein Ag18772
• Vollständiger Name: transient receptor potential cation channel, subfamily C, member 4 associated protein
• Berechnetes Molekulargewicht: 797 aa, 91 kDa
• Beobachtetes Molekulargewicht: 82 kDa
• GenBank-Zugangsnummer: BC013144
• Gene symbol: TRPC4AP
• Gene ID (NCBI): 26133
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TRPC4AP, also named as C20orf188 and TRRP4AP, is a substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. TRPC4AP participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. The calculated molecular weight of TRPC4AP is 91 kDa. Western blot analysis detected a protein of about 82 kDa expressed in several mouse cell lines and in a human promonocytic cell line.