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TRPM7 Rekombinanter Antikörper

TRPM7 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241191G7

Kat-Nr. : 84324-1-PBS

Synonyme

EC:2.7.11.1, Channel-kinase 1, Channel kinase 1, CHAK1, CHAK

Filter:
  • Western Blot (WB) analysis of various lysates using TRPM7 Recombinant antibody (84324-1-RR)

    WB analysis using 84324-1-RR (same clone as 84324-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84324-1-RR (TRPM7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84324-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84324-1-PBS bindet in WB, Indirect ELISA TRPM7 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name transient receptor potential cation channel, subfamily M, member 7
Berechnetes Molekulargewicht 213 kDa
Beobachtetes Molekulargewicht 220 kDa
GenBank-ZugangsnummerNM_017672
Gene symbol TRPM7
Gene ID (NCBI) 54822
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Transient receptor potential melastatin 7 (TRPM7), along with the closely related TRPM6, are unique channels that have dual operations: cation permeability and kinase activity. In contrast to the limited tissue distribution of TRPM6, TRPM7 is widely expressed among tissues and is therefore implicated in a variety of cellular functions physiologically and pathophysiologically. The discovery of TRPM7's unique structure imparting dual ion channel and kinase activities shed light onto novel and peculiar biological functions, such as Mg2+ homeostasis, cellular Ca2+ flickering, and even intranuclear transcriptional regulation by a cleaved kinase domain translocated to nuclei.