TRPV6 Polyklonaler Antikörper
TRPV6 Polyklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 31045-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
31045-1-PBS bindet in WB, Indirect ELISA TRPV6 und zeigt Reaktivität mit human, Maus
Getestete Reaktivität | human, Maus |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Polyklonal |
Typ | Antikörper |
Immunogen | TRPV6 fusion protein Ag34052 |
Vollständiger Name | transient receptor potential cation channel, subfamily V, member 6 |
Berechnetes Molekulargewicht | 87KD |
Beobachtetes Molekulargewicht | 75 kDa |
GenBank-Zugangsnummer | NM_018646 |
Gene symbol | TRPV6 |
Gene ID (NCBI) | 55503 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Antigen-Affinitätsreinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
TRPV6, also named as CAT1 or ECaC2, is a member of the transient receptor potential (TRP) family of membrane proteins. Unlike most TRP channels, TRPV6 and its closest relative, TRPV5, are calcium-selective channels. TRPV6 is highly expressed in the proximal intestine, placenta and exocrine tissues (PMID: 12869611). It is probably involved in calcium absorption in various tissues, including calcium reabsorption in kidney. TRPV6 is overexpressed in some cancers and exhibits oncogenic potential.