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TSPAN10 Polyklonaler Antikörper

TSPAN10 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14430-1-PBS

Synonyme

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  • Western Blot (WB) analysis of hTERT-RPE1 cells using TSPAN10 Polyclonal antibody (14430-1-AP)

    WB analysis of hTERT-RPE1 using 14430-1-AP (same clone as 14430-1-PBS)

    WB result of TSPAN10 antibody (14430-1-AP; 1:1200; incubated at room temperature for 1.5 hours) with sh-Control and sh-TSPAN10 transfected hTERT-RPE1 cells. This data was developed using the same antibody clone with 14430-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of hTERT-RPE1 cells using TSPAN10 Polyclonal antibody (14430-1-AP)

    IF Staining of hTERT-RPE1 cells using 14430-1-AP (same clone as 14430-1-PBS)

    IF result (nuclear and the base of cilia stain) of anti-TSPAN10 (14430-1-AP, 1:50) with human hTERT-RPE1 (MeOH fixation) cells by Dr. Moshe Kim. This data was developed using the same antibody clone with 14430-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

14430-1-PBS bindet in WB, IF/ICC, Indirect ELISA TSPAN10 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TSPAN10 fusion protein Ag5807
Vollständiger Name tetraspanin 10
Berechnetes Molekulargewicht 36.5 kDa
Beobachtetes Molekulargewicht36-40 kDa
GenBank-ZugangsnummerBC032802
Gene symbol TSPAN10
Gene ID (NCBI) 83882
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TSPAN10 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN10 belongs to the TSPANC8 subfamily, which also include TSPAN5, TSPAN14, TSPAN15, TSPAN17, and TSPAN33. It has been reported that TSPANC8 tetraspanins interact with ADAM10 and have a conserved function in the regulation of ADAM10 trafficking and activity, thereby positively regulating Notch receptor activation (PMID: 23091066; 23035126).