TSPAN2 Polyklonaler Antikörper

TSPAN2 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20463-1-PBS

Synonyme

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  WB analysis using 20463-1-AP (same clone as 20463-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20463-1-AP (TSPAN2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20463-1-PBS in a different storage buffer formulation.

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  WB analysis of HL-60 using 20463-1-AP (same clone as 20463-1-PBS)

  HL-60 cells were subjected to SDS PAGE followed by western blot with 20463-1-AP (TSPAN2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20463-1-PBS in a different storage buffer formulation.

• 

  IP experiment of HL-60 using 20463-1-AP (same clone as 20463-1-PBS)

  IP result of anti-TSPAN2 (IP:20463-1-AP, 4ug; Detection:20463-1-AP 1:500) with HL-60 cells lysate 960ug. This data was developed using the same antibody clone with 20463-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

20463-1-PBS bindet in WB, IP, Indirect ELISA TSPAN2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TSPAN2 fusion protein Ag14299
• Vollständiger Name: tetraspanin 2
• Berechnetes Molekulargewicht: 221 aa, 24 kDa
• Beobachtetes Molekulargewicht: 30-35 kDa
• GenBank-Zugangsnummer: BC021675
• Gene symbol: TSPAN2
• Gene ID (NCBI): 10100
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TSPAN2 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. It has been reported that TSPAN2 is involved in cell invasion and motility during lung cancer progression (PMID: 24726368). TSPAN2 enhances cell motility and invasiveness by assisting CD44 in scavenging intracellular reactive oxygen species.