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TSPO/PBR Polyklonaler Antikörper

TSPO/PBR Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15444-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of HEK-293 cells using TSPO/PBR Polyclonal antibody (15444-1-AP)

    WB analysis of HEK-293 using 15444-1-AP (same clone as 15444-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 15444-1-AP (TSPO/PBR antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15444-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse heart tissue using TSPO/PBR Polyclonal antibody (15444-1-AP)

    IHC staining of mouse heart using 15444-1-AP (same clone as 15444-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 15444-1-AP (TSPO/PBR antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15444-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse heart tissue using TSPO/PBR Polyclonal antibody (15444-1-AP)

    IHC staining of mouse heart using 15444-1-AP (same clone as 15444-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 15444-1-AP (TSPO antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15444-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

15444-1-PBS bindet in WB, IHC, Indirect ELISA TSPO/PBR und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TSPO/PBR fusion protein Ag7475
Vollständiger Name translocator protein (18kDa)
Berechnetes Molekulargewicht 18 kDa
Beobachtetes Molekulargewicht18 kDa
GenBank-ZugangsnummerBC001110
Gene symbol TSPO
Gene ID (NCBI) 706
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TSPO, also named Peripheral-type benzodiazepine receptor (PBR), encodes the translocator protein, belonging to tryptophan-rich sensory protein family. The protein is mainly localized in the outer mitochondrial membrane and expressed in steroid-synthesizing tissues (PMID:32881658, PMID:1326278). TSPO is involved in the translocation of cholesterol from the outer to inner mitochondrial membrane (PMID:21119734). In response to injury, TSPO has a upregulated expression in the peripheral nervous system (PMID:32423330, PMID:23251719). TSPO is also as a biomarker in a non-invasive procedure including detecting the inflammation in the heart and atherosclerotic plaques (PMID:24402571).