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TSSK2 Polyklonaler Antikörper

TSSK2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13806-1-PBS

Synonyme

Serine/threonine-protein kinase 22B, EC:2.7.11.1, DiGeorge syndrome protein G, DGS-G, DGSG

Filter:
  • Western Blot (WB) analysis of various lysates using TSSK2 Polyclonal antibody (13806-1-AP)

    WB analysis using 13806-1-AP (same clone as 13806-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13806-1-AP (TSSK2 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13806-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13806-1-PBS bindet in WB, Indirect ELISA TSSK2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TSSK2 fusion protein Ag4805
Vollständiger Name testis-specific serine kinase 2
Berechnetes Molekulargewicht 358 aa, 41 kDa
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerBC037781
Gene symbol TSSK2
Gene ID (NCBI) 23617
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TSSK2 (Testis-Specific Serine/Threonine Kinase 2) is a member of the TSSK family, predominantly expressed in the testis and involved in spermiogenesis and male fertility. It is localized in various regions of sperm, including the centrioles of post-meiotic spermatids, the tail, acrosomal regions, and the midpiece. TSSK2 plays a crucial role in sperm maturation by phosphorylating substrates such as TSKS and SPAG16L. Studies have shown that TSSK2 knockout mice exhibit infertility due to impaired spermatid elongation and sperm maturation. Additionally, TSSK2 is considered a promising target for reversible male contraception, with several potent inhibitors identified through high-throughput screening.