TTBK2 Rekombinanter Antikörper

• Featured Product
• KD/KO Validated

TTBK2 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

241456B4

Kat-Nr. : 84634-1-RR

Synonyme

241456B4, EC:2.7.11.1, KIAA0847, SCA11, tau tubulin kinase 2

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  WB analysis using 84634-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 84634-1-RR (TTBK2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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  WB analysis of HeLa using 84634-1-RR

  WB result of TTBK2 antibody (84634-1-RR; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-TTBK2 transfected HeLa cells.

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  Affinity and Kinetic Characterization of 84634-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84634-1-RR against Human TTBK2 were performed. The affinity constant is 0.14 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: PC-3-Zellen, HeLa-Zellen, HepG2-Zellen, L02-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

84634-1-RR bindet in WB, ELISA TTBK2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TTBK2 fusion protein Ag7108
• Vollständiger Name: tau tubulin kinase 2
• Berechnetes Molekulargewicht: 137 kDa
• Beobachtetes Molekulargewicht: 137-150 kDa
• GenBank-Zugangsnummer: BC071556
• Gene symbol: TTBK2
• Gene ID (NCBI): 146057
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TTBK2(tau tubulin kinase 2) plays an important role in the tau cascade and in spinocerebellar degeneration. The N-terminus of TTBK2 has a serine-threonine-tyrosine kinase domain, and a C-terminal region shows homology to TTBK1. TTBK1 and TTBK2 function as regulators of TDP-43 phosphorylation. TTBK1/2 may be attractive drug targets for therapeutic interventions in TDP-43 proteinopathies such as FTLD-TDP and ALS.(PMID:25473830).